Ֆարմացիայի ինստիտուտ
Institute of Pharmacy
In 2017 YSU Institute of Pharmacy with the mission of implementing educational, research and investment (innovation) functions was established.:
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Anna F. Mkrtchyan

Deputy Director of Scientific and Investment Affairs Candidate of Chemistry, Associate Professor | Chair of Pharmaceutical Chemistry and Pharmacognosy
Education
2008 - 2011: Ph.D student SPC “Armbiotechnology” of NAS RA
2003 - 2008: Graduate student of Department of Pharmaceutical Chemistry, Yerevan State University; qualification of Chemist – Pharmaceutist, Provisor’s.
1993 - 2003: Secondary school under Russian Military Unit 2037

Academic degree
2012 - PhD in Chemistry – «Сhiral octahedral charged complexes of СоШ as a new type of biomimetic catalysts for the asymmetric synthesis of important pharmacophore compounds», SPC «Armbiotechnology» SNPO NAS RA

Professional experience
2017 - present: Deputy Director for Science and Innovation of Institute of Pharmacy, YSU
2014 - present: Lecturer of Department of Pharmchemistry and Pharmacognosy)
2014 - present: Researcher of the Instutute of Pharmacy, YSU
2012 - 2014: Senior researcher of Faculty of Chemistry (now Institute of Pharmacy), YSU
2012 - 2014: Laboratory assistant of Department of Pharmaceutical Chemistry (now Department of Pharmchemistry and Pharmacognosy), YSU

Academic courses
Chemistry of Natural Compounds, Chiral Drugs

Scale of scientific interests
Asymmetric catalysis, biomimetic asymmetric synthesis of amino acids and biological active compounds

Participation in grant projects
ISTC Project # A-2289 (Sub-manager), 2017-2020
15T-1D260, (Researcher), 2015-2017
15RF-035 (Researcher), 2015-2017
Swiss National Science Foundation (SNSF) IZ73Z0_152360/1 (Researcher), 2014-2016
13-1D051, State Committee of Science MES RA (Researcher), 2013-2015
13RF-054, State Commitee of Science, (researcher), 2013-2015
ISTC Project # A-1677, (researcher), 2009-2012
YSSP-13-33, NFSAT & CRDF (scient. manager Anna Mkrtchyan), 2012-2013
Short Term Conference and Travel Grants Students and Young Academics in Armenia, 2012
RFFI #11-02-90903, NFSAT & CRDF (scient. manager AnnaMkrtchyan), 2013
ECSP-10-02_GRSP (scient. manager A. Mkrtchyan), 2010-2011

Membership
Member of Academic Counul of Institute of Pharmacy YSU
Member of Academic Counul of SPC «Armbiotechnology» NAS RA
Chairman of the consul of young science of SPC «Armbiotechnology» NAS RA
Member of consul of young science of RA
Member of public organization “Biotechnological Armenian Association” RA
Member of Young Chemists Association
Member of Armenian Biochemists Association

Awards
2017: An award from State Committee of science MESA as Highly effective young researchers
State Award 2015 of the Republic of Armenia in the sphere of exact and natural sciences "Effective small-scale production technology of a new generation of non-protein amino acids"
2014: An award from president for buying scientific equipments
2007: The Best Student award of the Yerevan State University

Languages
Armenian, Russian, English

anna_mkrtchyan@ysu.am

Latest Publications (35)
Ամինաթթուների ֆիզիկաքիմիական, օպտիկական հատկությունները և ստացման եղանակները
2018 | Book
Ուս. ձեռնարկ, ԵՊՀ հրատ., 2018, 40 էջ
Ashot Saghyan , Anna Mkrtchyan , Liana Hayriyan, Zorayr Mardiyan, Hayarpi Simonyan
Efficient method for the synthesis of novel enantiomericaly enriched derivatives of unsaturated amino acids
2018 | Thesis
16th Belgian Organic Synthesis Symposium, BOSS XVI. 2018, p. 342
Asymmetric synthesis of new heterocyclic analogs of alpha-aminopropionic acid and alpha-aminobutyric acid via Michael nucleophilic addition reactions
2018 | Thesis
16th Belgian Organic Synthesis Symposium, BOSS XVI, July 8-13, 2018, Brusseles, 343
Синтез энантиомерно обогащенной (s)-2-амино-5-(4-фторфенил)пент-4-еновой кислоты и ее α-аллилзамещенного аналога
2018 | Article
Химический Журнал Армении. 2018, 71, стр. 107-116
Mkrtchyan Anna F. , Saghyan Ashot S. , Mardiyan Zorayr Z., Parpart Silvio, Ehlers Peter, Petrosyan Andranik, Langer Peter
Synthesis of Optically Pure (S,E)-2-Amino-5-arylpent-4-enoic Acids by Heck Reactions of Nickel Complexes
2018 | Article
Synlett, 2018, 29, A-F pp.
Anna F. Mkrtchyan , Ashot S Saghyan , Liana A Hayriyan, Ani J Karapetyan, Zorayr Z Mardiyan, Hayarpi M Simonyan , Adonc Hovhannes
Efficient method for the synthesis of novel enatiomerically enriched derivatives of propargylglycine
2017 | Thesis
5th International Conference on Green CHemistry and Technology. 2017, p. 71
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Asymmetric synthesis of potential biologically active new heterocyclic analogs of (s)--alanine containing 3,4-substituted 5-thioxo-1,2,4- triazoles in the side-chain radical
2017 | Thesis
5th International Conference on Green Chemistry and Technology, 07/2017, Իտալիա, Հռոմ, 69
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Plasmids isolated from Pseudomonas aeroginosa soil strais carry the genes providing antibiotic resistance
2017 | Thesis
International Scientific Conference of Young Researchers. 2017, p. 88
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Asymmetric synthesis of enantiomerically enriched analog of α-aminobutyric acid containing heterocycle in the side chain radical
2017 | Thesis
IV International Scientific Conference of Young Researchers Biotechnology: Science and Practice, Sept. 28-30, 2017, Yerevan, Armenia, 141
Asymmetric synthesis and biological activity of novel heterocycle substituted analogues of α-aminobutyric acid
2017 | Thesis
VIII International Conference Modern Aspects of Rehabilitation In Medicine, 09/2017, Stepanakert, Artsakh, p. 344
Asymmetric synthesis of potential biologically active new analogs of (S)-alanine containing nitrogenous bases in the side-chain radical
2017 | Thesis
IV International scientific conference of young researcher, Biotechnology: Science and practice. 2017, p. 139
Z. Z. Mardiyan, L. A. Hayriyan, A. F. Mkrtchyan , A. X. Tsaturyan , A. J. Karapetyan, H. V. Adonc, H. M. Simonyan , S. Gh. Petrosyan , L. Yu. Sahakyan , A. S. Saghyan
Synthesis of optically pure (S)-2-amino-5-(3-fluorophenyl)-2-(prop-2-yn-1-yl)pent-4-yonic acid b y using Sonogashira reaction
2017 | Thesis
V научная конференция армянского химического общества, Актуальные задачи фундаментальной и прикладной химии. 2017, стр. 92
L. A. Hayriyan, A. F. Mrtchyan , Z. Z. Mardiyan, A. J. Karapetyan, H. V. Adonc, H. M. Simonyan , S. Gh. Petrosyan , L. Yu. Sahakyan , A. S. Saghyan
Asymmetric synthesis of enantiomerically enriched analogs of NiII complexes of (S)-allylglycine
2017 | Thesis
V научная конференция армянского химического общества, Актуальные задачи фундаментальной и прикладной химии, 2017, p. 62
Асимметрический синтез новых производных (S)-α-аланина, содержащих 3-замещенные 4-изобутил-5-тиоксо-1,2,4-триазолы в боковом радикале
2017 | Thesis
V научная конференция армянского химического общества, Актуальные задачи фундаментальной и прикладной химии. 2017, стр. 71
L. Hayriyan, A. Saghyan , H. Simonyan , A. Karapetyan, Z. Mardiyan, A. Mkrtchyan
Asymmetric synthesis of enantiomerically enriched new analogs of Ni II complexes of (S)-propargylglycine
2017 | Thesis
4th International Scientific Conference of Young Researchers on “Biotechnology. Science and Practice”. 2017, p. 138
H. V. Adonts, A. S. Saghyan , L. A. Hayriyan, A. F. Mkrtchyan
The synthesis of potentially active new enantiomerically enriched derivatives of glycine through click reaction
2017 | Thesis
V научная конференция армянского химического общества. 2017, стр. 49
A. S. Saghyan , L. A. Hayriyan, Z. Z. Mardiyan, A. F. Mkrtchyan
Five-year achievements in the field of the asymmetric synthesis of unsaturated amino acids
2017 | Thesis
V научная конференция армянского химического общества. 2017, стр. 6
New generations of optically active non-proteinogenic α-amino acids, synthesis and study
2016 | Article
Հայաստանի քիմիական հանդես, 2016, 69 N 1-2, 81-101 էջ
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Hayarpi M. Simonyan , Ashot S. Saghyan , Anna F. Mkrtchyan , Ani J. Karapetyan, Zorayr Z. Mardiyan, Liana A. Hayriyan
Synthesis of enantiomerically enriched amino acids containing acetylenic bond in the side-chain radical
2016 | Article
International Journal of Chemical Engineering and Applications, 2016, 7,6, pp. 413-416
Новые поколения оптически активных небелковых α-аминокислот, синтез и исследование
2016 | Article
Хим. журнал Армении, 2016, 69, 81-100
A. S. Saghyan , S. Gh. Petrosyan , A. V. Geolchanyan, A. F. Mkrtchyan , Z. Z. Mardiyan
Asymmetric synthesis of new enantiomerically enriched a-amino acids
2015 | Thesis
International Congress on Heterocyclic Chemistry, “KOST-2015”. 2015, p. 63
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Silvio Parpart, Andranik Petrosyan, Syed Jawad Ali Shah, Raji Akeem Adewale, Peter Ehlers, Tatevik Grigoryan, Anna F. Mkrtchyan , Zorayr Z. Mardiyan, Ani J. Karapetyan, Avetis H. Tsaturyan , Ashot S. Saghyan , Jamshed Iqbal, Peter Langer
Synthesis of optically pure (S)-2-amino-5-arylpent-4-ynoic acids by Sonogashira reactions and their potential use as highly selective potent inhibitors of aldose reductase
2015 | Article
RSC Advances. 2015, 5, p. 107400-107412
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Мкртчян А. Ф. , Геолчанян А. В., Симонян А. М. , Петросян С. Г. , Сагиян А. С. , Малеев В. И., Белоконь Ю. Н., Хрусталев В. Н.
Синтез положительно заряженных комплексов CoIII и их исследование в качестве хиральных катализаторов в реакциях асимметрического генерирования C-C связи
2015 | Article
Химический Журнал Армении. 2015, 68, стр. 108-121
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А. Ф. Мкртчян , З. З. Мардиян, А. Ж. Карапетян, А. С. Погосян, С. Г. Петросян , А. М. Симонян , А. О. Цатурян , А. С. Сагиян
Асимметрический синтез новыx энантиомерно обогащенныx ненасыщенныx α-аминокислот
2015 | Article
Хим. журн. Армении, 2015, № 3, сс. 403-412
A. S. Saghyan , A. F. Mkrtchyan , S. G. Petrosyan , J. A. Yedoyan, H. M. Simonyan , A. V. Geolchanyan, P. Langer, A. M. Petrosyan
Asymmetric synthesis of new enantiomerically enriched a-amino acids
2015 | Thesis
14th International Congress on Amino Acids, Peptides and Proteins, Austria, Vienna, august 3-7, 2015, Amino Acids, v. 47, №8, p. 1633(Amino Acids 2015, Volume 47, Issue 8, pp. 1607-1696)
А. Ф. Мкртчян , А. Ж. Карапетян, С. Г. Петросян, А. М. Симонян , А. О. Цатурян, А. С. Сагиян, З. З. Мардиян, А. С. Погосян
Асимметрический синтез новых энантиомерно обогащенных ненасыщенных α-аминокислот
2015 | Article
Химический Журнал Армении, 2015, 68, 403-412 стр.
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А. С. Сагиян , Дж. А. Едоян, А. Ф. Мкртчян , Г. Ц. Овсепян, А. О. Цатурян , П. Лангер
Асимметрический синтез новыx энантиомерно обогащенныx α-замещенныx аналогов (S)-пропаргилглицина
2014 | Article
Хим. журн. Армении, 2014, № 1, сс. 67-74
А. С. Сагиян , С. Г. Петросян , А. В. Геолчанян, А. Ф. Мкртчян , А. М. Симонян , Е. Г. Пароникян, П. Лангер
Асимметрический синтез энантиомерно обогащенных аналогов (R)-цистеина
2014 | Article
Химический журнал Армении, 2014, т. 67, №4, сс. 397-404
A. S. Saghyan , H. M. Simonyan , S. G. Petrosyan , A. F. Mkrtchyan , L. V. Khachatryan, A. V. Geolchanyan, M. A. Samvelyan, T. V. Ghochikyan, N. Kelzhanova, A. T. Saginayev, P. Langer
Asymmetric Synthesis of Enantiomerically Enriched α-Amino Acids Containing Furans, Thiophenes and 1,2,4-Triazoles in the Side-Chain
2014 | Article
Z. Naturforsch, 2014, 69b, 451 – 460
V. I. Maleev, T. V. Skrupskaya, L. V. Yashkina, A. F. Mkrtchyan , A. S. Saghyan , M. M. Il’in, D. A. Chusov
Aza-Diels–Alder reaction catalyzed by novel chiral metalocomplex Brønsted acids
2013 | Article
Tetrahedron: Asymmetry, 24, 2013, 178-183
Ashot S. Saghyan , Gnel M. Mkrtchyan, Ani S. Dadayan , Satenik G. Petrosyan , Arpine V. Geolchanyan, Hayarpi M. Simonyan , Anna F. Mkrtchyan , Satenik Mkrtchyan, Ashot Gevorgyan, Viktor O. Iaroshenko, Peter Langer
Asymmetric synthesis of enantiomerically enriched (S)-a-aminopropionic acids containing heterocyclic side chains
2013 | Article
Tetrahedron: Asymmetry 24 (2013) 229–232
N. Yu. Kuznetsov, V. I. Maleev, V. N. Khrustalev, A. F. Mkrtchyan , I. A. Godovikov, T. V. Strelkova, Y. N. Bubnov
A New Method of Synthesis of 6‐Substituted Piperidine‐2,4‐diones from Homoallylamines
2012 | Article
Eur. J. Org. Chem, 2012, v. 2012, р. 334-344
Ю. Н. Белоконь, В.А. Ларионов, А. Ф. Мкртчян , В. Н. Хрусталев, А. Ниджланд, А. С. Сагиян , И. А. Годовиков, А. С. Перегудов, К. К. Бабиевский, Н. С. Иконников, В. И. Малеев
Новый тип катализаторов асимметрического образования связей С—С на основе хиральных стереохимически инертных катионных комплексов СoIII
2012 | Article
Изв.Акад. Наук, 2012, 2231-2240
Ashot S. Saghyan , Ani. S. Dadayan , Slavik. A. Dadayan , Anna F. Mkrtchyan , Arpine V. Geolchanyan , Luiza L. Manasyan , Henry R. Ajvazyan, Victor N. Khrustalev, Hasmik H. Hambardzumyan, Victor I. Maleev
Very fast asymmetric synthesis of amino acids via NiII complexes based on new fluorine containing chiral auxiliaries
2010 | Article
Tetrahedron: Asymmetry, 2010, vol. 21, pp. 2956-2965
V. I. Maleev, T. V.Scrupskaya, T. F. Saveleva, A. S. Saghiyan, A. F. Mkrtchyan
Lithium salts of chiral metallocomplex anions as catalysts for asymmetric trimethylsilylcyanation of aldehydes
2010 | Article
Russ. Chem. Bull., 2010, p. 598-604