Ֆարմացիայի ինստիտուտ
Institute of Pharmacy
In 2017 YSU Institute of Pharmacy with the mission of implementing educational, research and investment (innovation) functions was established.:
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Gayane E. Avetisova

Candidate of Biology, Assistant | Chair of Pharmaceutical Chemistry and Pharmacognosy
Education
1979-1984 Yerevan State University, Faculty of Biology, Department of Biochemistry

Academic degree, rank
PhD in Biology

Dissertation/thesis topic
"Obtaining of Highly Active Strains Producers of L-Valine at Brevibacterium flavum. Technology of Biosynthesis L-Valine in Industrial Conditions" /Speciality Biotechnology, 2004

Scope of scientific interests
Biotechnology, Microbiology, Genetics

Lectures delivered
Biotechnology

Professional activities
2017 to present: Assistant of Chair of Pharmchemistry and Pharmacognosy of Institute of Pharmacy of Yerevan State University
2016: Assistant of Chair of Pharmchemistry and Pharmacognosy of Faculty of Pharmacy and Chemistry of Yerevan State University
2015: Assistant of Chair of Pharmacy of Faculty of Pharmacy and Chemistry of Yerevan State University
2006-2014: Assistant of Chair of Pharmaceutical Chemistry of Faculty of Chemistry of Yerevan State University
2010-2013: Deputy director of «SIS-95» Ltd
2010 to present: Leading researcher of Scientific and Production Center «Armbiotechnology» NAS RA
2008-2009: Leading researcher of «Scientific Research Institute of Biotechnology» CJSC
2005-2009: Scientific secretary of «Scientific Research Institute of Biotechnology» CJSC
2008 to present: Secretary of scientists’ Board of Specialized Council 018 Biotechnology
2005-2007: Senior researcher of Scientific Research Institute of «Biotechnology» CJSC
1999-2001: Head of Marketing Department of Scientific Research Institute of «Biotechnology» CJSC
1994-2004: Researcher of Scientific and Production Union «Armbiotechnology»
1984-1993: Junior researcher of Scientific Research Technological Institute of Amino Acids

Membership
Specialized Council 018 Biotechnology
Biotechnological Association of Armenian
Armenian Microbiological Association
Federation of European Microbiological Societies (FEMS)
Registration Commission of Pesticides and Agrochemicals for Food Safety Inspection Body of RA

Awards/Honors
2006: Certificate of Honour of the «Scientific Research Institute of Biotechnology» CJSC
2006: Certificate of Honour of Ministry of Trade and Industry of RA
2013: Certificate of Merit of NAS RA

Grants/Contracts
Agreement of scientific research and experimental work between the Scientific Research Institute of Applied Microbiology of Chinese Academy of Agricultural Sciences of Xinjiang Provinceand "Scientific Research Institute of Biotechnology" CJSC (2001-2004)
ISTC #А-683(2002-2005)
0590 (2005-2007)
465 (2008-2010)
ISTC #A-1677 (2009-2012)
ISTC #А-1868 (2010-2012)
AB16-52 (2017-2019)
21T-2I229 (2021-2024)

Supervisor of PhD dissertations
G.00.14 - "Biotechnology", 2013
G.00.07 - "Microbiology. Biotechnology ", 2017

Computer skills
Word, Excel, Access, PowerPoint, Internet

Language skills
Armenian, Russian, English

E-mail
avetisovagayane@ysu.am

Latest Publications (32)
L. Melkonyan , A. Toplaghaltsyan, S. Keleshyan, Zh. Karapetyan, G. Avetisova , G. Tsarukyan
Determination of Enzymatic Activity of Nitrogen-Fixing Bacteria Isolated from Saline Soils of Armenia
2021 | Thesis
International Scientific and Practical Conference “BIOTECHNOLOGY: Science and Practice. Innovation and Business”, October 20-22, 2021, Yerevan, Armenia, pp. 78-79
L. Melkonyan , G. Avetisova , G. Tsarukyan, S. Keleshyan, Zh. Karapetyan, A. Toplaghaltsyan, V. Ghochikyan
Influence of Vitamins on L-Tryptophan Production by Brevibacterium flavum
2021 | Article
International Scientific and Practical Conference “BIOTECHNOLOGY: Science and Practice. Innovation and Business”. October 20-22, 2021, Yerevan, Armenia, pp. 82-86
L. Melkonyan , G.Avetisova , A. Toplaghaltsyan, G. Tsarukyan, S. Keleshyan, Zh. Karapetyan, V. Ghochikyan
Co-cultivation of L-Tryptophan-producing Strain Brevibacterium flavum and Azotobacter vinelandii as an Alternative Method for Indole-3-Acetic Acid Production
2021 | Article
International Scientific and Practical Conference “BIOTECHNOLOGY: Science and Practice. Innovation and Business”. October 20-22, 2021, Yerevan, Armenia, pp. 6-10
L. Melkonyan , A. Ferreira, S. Carapinha, B. Ribeiro, D. Figueiredo, G. Avetisova , L. Gouveia
Biostimulant and biopesticide potential of microalgae growing in piggery wastewater
2021 | Article
Environmental Advances (Elsevier /Directory of Open Access Journals, DOAJ/), 2021, v. 4, 100062, doi.org/10.1016/j.envadv.2021.100062
L. Melkonyan , A. Ferreira, S. Carapinha, B. Ribeiro, D. Figueiredo, G. Avetisova , L. Gouveia
Assessment of biostimulant and biopesticide potential of microalgae following piggery wastewater treatment
2020 | Thesis
International Conference “AlgaEurope 2020”, December 01-04, 2020, ONLINE, pp. 17-19
L.H. Melkonyan , A.M. Paloyan, A.V. Mkhitaryan, A.A. Hambardzumyan, G. Avetisova
New α-amylase from Bacillus sp. MDC 3500 strain
2019 | Thesis
Designer Biology 2019 conference “From proteins and cells to scaffolds & materials in Europe”. July 31- August 2, 2019, Newcastle, UK, p. 47
L. Melkonyan , S. Keleshyan, Zհ. Karapetyan, A. Toplaghaltsyan, G. Avetisova , G. Tsarukyan, V. Ghochikyan
Agrobacterium sp. as nitogen-fixing bacteria: effect of osmo-resistant strains on the growth of plants in saline soils of Armenia
2019 | Thesis
International Conference “Microbes: biology and application”. October 9-11, 2019, Yerevan, Armenia, pp. 31-32
L. Melkonyan , A. Ferreira, B. Ribeiro, M.L.A. Tavares, J. Vladic, S. Vidovic, D. Cvetkovic, G. Avetisova , V. Goginyan, L. Gouveia
Scenedesmus obliquus microalga-based biorefinery - from brewery effluent to bioactive compounds, biofuels and biofertilizers – aiming a circular bioeconomy
2019 | Article
Biofuels, Bioproducts and Biorefineries, 2019, v. 13, №5, pp.1169-1186, doi.org/10.1002/bbb.2032
Л.О. Мелконян , С.К. Келешян, Ж.В. Карапетян, А.Г. Топлакалцян, Г.Е. Аветисова , В.Т. Кочикян
Характеристика микрофлоры засоленных почв Армении
2019 | Article
Хранение и переработка сельхозсырья, 2019, №1, cc. 76-85, DOI: 10.36107/spfp.2019.81
L. Melkonyan , A. Ferreira, A. Reis, S. Vidovic, J. Vladic, S. Gkelis, G. Avetisova , R. Congestri, G. Acién, R. Muñoz, P. Collet, L. Gouveia
Combining Microalgae-Based Wastewater Treatment with Biofuel and Bio-Based Production in the Frame of a Biorefinery. In: Hallmann A., Rampelotto P. (eds) Grand Challenges in Algae Biotechnology
2019 | Book
Grand Challenges in Biology and Biotechnology. Springer, Cham, 2019, pp 319-369, DOI:10.1007/978-3-030-25233-5_9 (ISBN 978-3-030-25232-8; ISBN 978-3-030-25233-5 /eBook/)
A. Ferreira, B. Ribeiro, J. Vladic, S. Vidovic, D. Cvetkovic, L. Melkonyan , G. Avetisova , AF. Ferreira, M. Costa, A. Reis, L. Gouveia
Industrial wastewater-grown Scenedesmus obliquus biomass-to-fuels and biofertilizers production: an integrative approach
2019 | Thesis
IWA Conference on Algal Technologies and Stabilization Ponds for Wastewater Treatment and Resource Recovery (IWAlgae2019), July 1-2, 2019, Valladolid, Spain, 2.B.8.
A. Ferreira, S. Carapinha, J. Vladic, S. Vidovic, D. Cvetkovic, L. Melkonyan , G. Avetisova , L. Gouveia
Tiny Microalgae For Huge Applications. Biorefinery Approach
2019 | Thesis
1st International Conference on Advanced Production and Processing, October 10-11, 2019, Novi Sad, Serbia. p. 251
L. Melkonyan , A. Paloyan, A. Hambardzumyan, G. Avetisova , A. Mkhitaryan, A. Sargsyan, S. Stepanyan, S. Arabachyan, A. Saghyan
Study of some metals effect on a-amylase activity of Bacillus amyloliquefaciens MDC 1974 strain
2018 | Thesis
43rd FEBS Congress. July 7-12, 2018, Prague, Czech Republic, FEBS Open Bio 8 (Suppl.S1) p.178, DOI: 10.1002/2211-5463.12453
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L. Melkonyan , A. Paloyan, A. Sargsyan, T. Arakelyan, M. Izmailyan, G. Avetisova , A. Hambardzumyan, A. Saghyan
Optimization of fermentation condition for a-amylase production
2018 | Thesis
43rd FEBS Congress. July 7-12, 2018, Prague, Czech Republic, FEBS Open Bio 8 (Suppl.S1) p. 177, DOI: 10.1002/2211-5463.12453
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L. Melkonyan , G. Avetisova , A. Chakhalyan, S. Keleshyan, Zh. Karapetyan, S. Stepanyan, A. Toplaghaltsyan, A. Saghyan
Biotechnological approaches for obtaining of new complex biopreparation for organic agriculture
2017 | Thesis
7th Congress of European Microbiologists (FEMS). July 9-13, 2017, Valencia, Spain, 337
S. K. Keleshyan, Zh.V. Karapetyan, A.Kh. Chakhalyan, N.A. Hovhannisyan, G.Ye. Avetisova , M.B. Chitchyan, G.G. Oganezova, M.A. Melkumyan, N.S. Avetisyan, L.H. Melkonyan
Influence of Glutamate Dehydrogenase Activity on L-Proline Synthesis
2017 | Article
Applied Biochemistry and Microbiology, 2017, 53, 5, 470-476
К. М. Сарикян, Г. Ж. Саргсян, Г. Е. Аветисова , Л. О. Мелконян
Новое биоудобрение «Азоцеовит-1» для органического овощеводства и его испытание на посадках перца и баклажана в Армении
2017 | Article
ІІІ Международная научно-практическая конференция «Неделя науки в Крутах – 2017». 13-14 марта, 2017, Круты, Черниговская обл., Украина, 264-271
A. Toplaghaltsyan, S. Keleshyan, Zh. Karapetyan, N. Khachaturian, G. Avetisova , L. Melkonyan , S. Stepanyan
Screening of lactic acid bacteria with a wide spectrum of antifungal activity
2017 | Thesis
4th International Scientific Conference of Young Researchers “Biotechnology: Science and Practice”. 2017, 66-67 pp.
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G. Avetisova , L. Melkonyan , S. Stepanyan, K. Sarikyan, V. Ghochikyan, S. Keleshyan, Zh. Karapetyan, A. Toplaghaltsyan
Effect of " Ecobiofeed+ " Biopreparation on Eggplant (Solanum Melongena S.)
2017 | Thesis
4th International Scientific Conference of Young Researchers “Biotechnology: Science and Practice”. 2017, p. 63
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Мелконян Л. О. , Степанян С. Х., Аветисова Г. Е. , Сарикян К. М.
Новый биопрепарат «экобиофид+» для органического земледелия и его испытание на посадках томатов в Армении
2017 | Article
Innovative approaches and perspective ideas of young scientists in agrarian sciences. The proceedings of the international scientific-practical conference of young scientist. 2017, 384-387pp.
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К. М. Сарикян, Г. Ж. Саргсян, Г. Е. Аветисова , Л. О. Мелконян
Новое биоудобрение «Азоцеовит-1» для органического овощеводства и его испытание на посадках перца и баклажана в Армении
2017 | Article
Неделя науки в Крутах -2017. 2, стр. 264-271
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А. Х. Чахалян, С. К. Келешян, Ж. В. Карапетян, А. Г. Давтян, Г. Е. Аветисова , Л. О. Мелконян , А. С. Дадаян, А. С. Сагиян
Изучение ингибирующих свойств новых небелковых аминокислот и отбор эффективных аналогов L-аминокислот для селекции высокоактивных штаммов-продуцентов
2016 | Article
Прикладная биохимия и микробиология (Applied Biochemistry and Microbiology), 2016, 52, стр. 62–67
L. H. Melkonyan , G. H. Tepanosyan, G. Ye. Avetisova , A. Kh. Chakhalyan, S. Gh. Keleshyan, Zh. V. Karapetyan
The nitrogen-fixing strain for biopreparation
2016 | Article
Biological Journal of Armenia, 2016, 68, pp. 65-68
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Chakhalyan A. Kh., Keleshyan S. Gh., Karapetyan Zh. V., Davtyan A. G., Avetisova G. Y. , Melkonyan L. H. , Dadayan A. S. , Saghyan A. S.
The inhibitory properties of new non-protein amino acids and the screening of effective analogs of L-amino acids for the selection of highly active strain-producers
2016 | Article
Applied Biochemistry and Microbiology, 2016, v. 52, № 1, p. 51-55
G. Ye. Avetisova , L. H. Melkonyan , A. Kh. Chakhalyan, S. Gh. Keleshyan, A. S. Saghyan
Selection of new highly active L-alanine producer strains of Brevibacterium flavum and comparison of their activity in alanine synthesis
2014 | Article
Russian Journal of Genetics: Applied Research, 2014, 4, 1, 23-26
Ազոտ ֆիքսող մանրէների հիման վրա կոմպլեքսային կենսաբանական պարարտանյութի ստացման եղանակ (տարբերակներ)
2013 | Patent
ՀՀ Արտոնագիր №2713A, 25.02.2013 - 5 էջ
Селекция новых высокоактивных штаммов–продуцентов L–аланина у Brevibacterium flavum и сравнительная характеристика их аланинcинтезирующей активности
2013 | Article
Вавиловский журнал генетики и селекции, 2013, 17, 3, 430–434
Л. О. Мелконян , А. А. Амбарцумян, Г. Е. Аветисова , А. Х. Чахалян, А. С. Сагиян
Показатели материально-энергетического баланса биосинтеза L-аланина Brevibacterium flavum
2013 | Article
Биотехнология, 2013, 3, 47-50
Study of regulation of some key enzymes of L-alanine biosynthesis by Brevibacterium flavum producer strains
2013 | Article
Applied Biochemistry and Microbiology, 2013, 49, 2, 120-124
L-ալանինի ստացման եղանակ
2012 | Patent
ՀՀ Արտոնագիր №2691A, 2012
A. Chakhalyan, G. Avetisova , A. Saghiyan , L. Chil-Akopyan, L. Melkonyan , R. Gevorkyan, H. Sargsyan, L. Ghazarian
Zeolites in complex nitrogen biofertilizers
2008 | Article
ELSEVIER, Zeolites and related materials – trends, targets and challenges, 2008, 521-524
G. Ye. Avetisova , A. A. Hambardzumyan, Sh. M. Kocharyan, A. S. Saghyan
Расчет максимального коэффициента продуктивности и других показателей процесса биосинтеза валина культурой Brevibacterium flavum (Brevibacterium flavum բջիջներով վալինի կենսասինթեզի պրոցեսի արտադրողականության մաքսիմալ գործակցի և այլ գործակցի և այլ գործակիցների հաշվարկը)
2003 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 2003, #2, էջ 94-99 (ռուսերեն)
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